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Statistical Aspects Of The Design And Analysis Of Clinical Trials

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Statistical Aspects Of The Design And Analysis Of Clinical Trials
https://www.amazon.com/Statistical-Aspects-Analysis-Clinical-Revised/dp/1860944418
http://www.worldscientific.com/worldscibooks/10.1142/p321#t=aboutBook
Fully updated, this revised edition describes the statistical aspects of both the design and analysis of trials, with particular emphasis on the more recent methods of analysis.
About 8000 clinical trials are undertaken annually in all areas of medicine, from the treatment of acne to the prevention of cancer. Correct interpretation of the data from such trials depends largely on adequate design and on performing the appropriate statistical analyses. This book provides a useful guide to medical statisticians and others faced with the often difficult problems of designing and analysing clinical trials
Contents:
An Introduction to Clinical Trials
Treatment Allocation, the Size of Trials and Reporting Results
Monitoring Trial Progress: Outcome Measures, Compliance, Dropouts and Interim Analyses
Basic Analyses of Clinical Trials, the Generalised Linear Model and the Economic Evaluation of Trials
Simple Approaches to the Analysis of Longitudinal Data from Clinical Trials
Multivariate Normal Regression Models for Longitudinal Data from Clinical Trials
Models for Non-Normal Longitudinal Data from Clinical Trials
Survival Analysis
Bayesian Methods Longitudinal Data
Meta-Analysis
First published 1999Revised edition 2004.

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